Diagnosis of endometriosis by detection of nerve fibres in an endometrial biopsy: a double blind study | Zendy

Moamar AlJefout | Zendy; Gabrielle Dezarnaulds | Zendy; Michael Cooper | Zendy; Natsuko Tokushige | Zendy; Georgina Luscombe | Zendy; Robert Markham | Zendy; Ian S. Fraser | Zendy

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Diagnosis of endometriosis by detection of nerve fibres in an endometrial biopsy: a double blind study

Author(s) -

Moamar AlJefout,

Gabrielle Dezarnaulds,

Michael Cooper,

Natsuko Tokushige,

Georgina Luscombe,

Robert Markham,

Ian S. Fraser

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep275

Subject(s) - endometriosis , medicine , endometrial biopsy , laparoscopy , biopsy , endometrium , double blind , gynecology , radiology , obstetrics , pathology , alternative medicine , placebo

Diagnosis of endometriosis currently requires a laparoscopy and this need probably contributes to the considerable average delay in diagnosis. We have reported the presence of nerve fibres in the functional layer of endometrium in women with endometriosis, which could be used as a diagnostic test. Our aim was to assess efficacy of nerve fibre detection in endometrial biopsy for making a diagnosis of endometriosis in a double-blind comparison with expert diagnostic laparoscopy.

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