Lower incidence of hypertensive complications during pregnancy in patients treated with low-dose aspirin during in vitro fertilization and early pregnancy | Zendy

Marieke J. Lambers | Zendy; E. Groeneveld | Zendy; Diederik A. Hoozemans | Zendy; R. Schats | Zendy; Roy Homburg | Zendy; Cornelis B. Lambalk | Zendy; Peter G.A. Hompes | Zendy

Open Access

Lower incidence of hypertensive complications during pregnancy in patients treated with low-dose aspirin during in vitro fertilization and early pregnancy

Author(s) -

Marieke J. Lambers,

E. Groeneveld,

Diederik A. Hoozemans,

R. Schats,

Roy Homburg,

Cornelis B. Lambalk,

Peter G.A. Hompes

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep245

Subject(s) - pregnancy , medicine , aspirin , placebo , obstetrics , in vitro fertilisation , incidence (geometry) , randomized controlled trial , eclampsia , preeclampsia , gynecology , surgery , genetics , alternative medicine , physics , pathology , optics , biology

The use of aspirin during in vitro fertilization (IVF) has been investigated for its effect on pregnancy rates after IVF. In most of these studies, aspirin administration was then prolonged throughout the first trimester of pregnancy. By inhibiting vasoconstriction, the use of low-dose aspirin in the first trimester could influence placentation and therefore prevent or delay development of hypertensive pregnancy complications, such as pregnancy-induced hypertension (PIH) and pre-eclampsia (PE).

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