The relationships between AMH, androgens, insulin resistance and basal ovarian follicular status in non-obese subfertile women with and without polycystic ovary syndrome | Zendy

Luciano G. Nardo | Zendy; Allen P. Yates | Zendy; Stephen A. Roberts | Zendy; Philip A. Pemberton | Zendy; Ian Laing | Zendy

Open Access

The relationships between AMH, androgens, insulin resistance and basal ovarian follicular status in non-obese subfertile women with and without polycystic ovary syndrome

Author(s) -

Luciano G. Nardo,

Allen P. Yates,

Stephen A. Roberts,

Philip A. Pemberton,

Ian Laing

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep225

Subject(s) - polycystic ovary , anti müllerian hormone , medicine , insulin resistance , antral follicle , endocrinology , homeostatic model assessment , free androgen index , testosterone (patch) , folliculogenesis , ovarian reserve , follicular phase , hormone , insulin , biology , infertility , pregnancy , lactation , genetics

Hyperandrogenaemia and insulin resistance are prominent features of polycystic ovary syndrome (PCOS) and influence the process of folliculogenesis in women with the endocrinopathy. Anti-Müllerian hormone (AMH) levels are elevated in women with PCOS and studies including IVF subjects have shown that this is a reliable marker of ovarian performance. The aims of this prospective study were to assess the relationship between insulin resistance, androgens and AMH, and whether AMH contributes to altered folliculogenesis in non-obese women with PCOS.

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