Oct-4 regulates the expression of Stella and Foxj2 at the Nanog locus: implications for the developmental competence of mouse oocytes | Zendy

Maurizio Zuccotti | Zendy; Valeria Merico | Zendy; Lucia Sacchi | Zendy; Michele Bellone | Zendy; Thore C. Brink | Zendy; Mario Stefanelli | Zendy; Carlo Alberto Redi | Zendy; Riccardo Bellazzi | Zendy; James Adjaye | Zendy; Silvia Garagna | Zendy

Open Access

Oct-4 regulates the expression of Stella and Foxj2 at the Nanog locus: implications for the developmental competence of mouse oocytes

Author(s) -

Maurizio Zuccotti,

Valeria Merico,

Lucia Sacchi,

Michele Bellone,

Thore C. Brink,

Mario Stefanelli,

Carlo Alberto Redi,

Riccardo Bellazzi,

James Adjaye,

Silvia Garagna

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep191

Subject(s) - biology , oocyte , oogenesis , genetics , microbiology and biotechnology , chromatin , homeobox protein nanog , gene , embryo , embryonic stem cell , induced pluripotent stem cell

Our knowledge of what determines the mammalian oocyte developmental competence is meagre. By comparing the transcriptional profiles of developmentally competent surrounded nucleolus (SN) and incompetent not surrounded nucleolus (NSN) mouse MII oocytes, we recently demonstrated that Oct-4 and Stella are key factors in the establishment of the oocytes' developmental competence.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research