Expression of selected tumor suppressor and oncogenes in endometrium of women with endometriosis | Zendy

Piotr Laudański | Zendy; Jacek Szamatowicz | Zendy; Oksana Kowalczuk | Zendy; Mariusz Kuźmicki | Zendy; Marcin Grabowicz | Zendy; L Chyczewski | Zendy

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Expression of selected tumor suppressor and oncogenes in endometrium of women with endometriosis

Author(s) -

Piotr Laudański,

Jacek Szamatowicz,

Oksana Kowalczuk,

Mariusz Kuźmicki,

Marcin Grabowicz,

L Chyczewski

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep175

Subject(s) - endometriosis , pten , cancer research , oncogene , endometrium , pi3k/akt/mtor pathway , immunohistochemistry , kras , medicine , biology , cancer , signal transduction , cell cycle , biochemistry , colorectal cancer

It is becoming increasingly evident that the eutopic endometrium of women with endometriosis shows certain genetic alterations which are not found in the endometrium of disease-free women. The aim of the study was to compare the expression level of mammalian target of rapamycin (mTOR) tumor suppressor and oncogene-related genes in the endometrium of women with and without endometriosis as well as in ovarian endometriosis.

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