Pharmacokinetics of repeated doses of misoprostol
Author(s) -
Ernest Hung Yu Ng,
Horst Schweer,
Sung Won Lee,
P. C. Ho
Publication year - 2009
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dep108
Subject(s) - misoprostol , medicine , pharmacokinetics , obstetrics , obstetrics and gynaecology , mifepristone , medical abortion , intravaginal administration , abortion , gynecology , anesthesia , vagina , pregnancy , pharmacology , surgery , genetics , biology
Misoprostol is widely used in obstetrics and gynaecology for medical abortion, cervical priming and induction of labour. To aid the design of effective and safe regimens, we have investigated the pharmacokinetic parameters after the vaginal or sublingual administration of repeated doses of 400 microg of misoprostol.
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