Luteal phase empirical low molecular weight heparin administration in patients with failed ICSI embryo transfer cycles: a randomized open-labeled pilot trial | Zendy

Bülent Urman | Zendy; Barış Ata | Zendy; Kayhan Yakın | Zendy; C. Alataş | Zendy; Sercan Aksoy | Zendy; Ramazan Mercan | Zendy; Başak Balaban | Zendy

Open Access

Luteal phase empirical low molecular weight heparin administration in patients with failed ICSI embryo transfer cycles: a randomized open-labeled pilot trial

Author(s) -

Bülent Urman,

Barış Ata,

Kayhan Yakın,

C. Alataş,

Sercan Aksoy,

Ramazan Mercan,

Başak Balaban

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep086

Subject(s) - heparin , embryo transfer , luteal phase , trophoblast , in vitro fertilisation , randomized controlled trial , medicine , embryo , low molecular weight heparin , andrology , gynecology , pregnancy , biology , fetus , hormone , genetics , placenta

The pathology underlying recurrent implantation failures (RIF) is not clear and treatment options proposed are generally not evidence based. Although the effect of heparin on trophoblast biology has not been studied extensively, given the available data suggesting a possible beneficial effect of heparin on embryo implantation, we decided to undertake this pilot study.

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