Polymorphic expression of DAZ proteins in the human testis
Author(s) -
Byunghyuk Kim,
Youngbin Lee,
Yeonwha Kim,
Kyoung Ho Lee,
Sunhye Chun,
Kunsoo Rhee,
Ju Tae Seo,
Soo Woong Kim,
JaeSeung Paick
Publication year - 2009
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dep032
Subject(s) - biology , microbiology and biotechnology , y chromosome , gene , complementary dna , polymerase chain reaction , genetics , homology (biology) , cloning (programming) , sequence analysis , computer science , programming language
DAZ is a male infertility gene located at the AZFc region of the Y chromosome. There are four copies of the DAZ gene that share a strong homology but are not identical to one another. In the present study, we carried out cDNA cloning and immunoblot analyses to determine whether all of the DAZ genes are actively expressed in the human testis.
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