Decoy receptor 3 expression during the menstrual cycle and pregnancy, and regulation by sex steroids in endometrial cells in vitro | Zendy

HsinFu Chen | Zendy; JauShiuh Chen | Zendy; ChiaTung Shun | Zendy; Yuan-Fu Tsai | Zendy; HongNerng Ho | Zendy

Open Access

Decoy receptor 3 expression during the menstrual cycle and pregnancy, and regulation by sex steroids in endometrial cells in vitro

Author(s) -

HsinFu Chen,

JauShiuh Chen,

ChiaTung Shun,

Yuan-Fu Tsai,

HongNerng Ho

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep028

Subject(s) - decidua , endocrinology , medicine , luteal phase , progesterone receptor , endometrium , biology , menstrual cycle , mifepristone , decidual cells , pregnancy , estrogen receptor , andrology , placenta , hormone , fetus , cancer , breast cancer , genetics

Decoy receptor 3 (DcR3) is a soluble receptor belonging to the tumor necrosis factor receptor superfamily and can inhibit Fas ligand-induced apoptosis. DcR3 is related to carcinogenesis, but is found in human gestational tissues, where the function is uncertain. We aimed to determine DcR3 expression and regulation in endometrial cells in vitro, and throughout the menstrual cycle and pregnancy in vivo.

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