Superficial ovarian cortex vascularization is inversely related to the follicle reserve in normal cycling ovaries and is increased in polycystic ovary syndrome | Zendy

Francisco Delgado-Rosas | Zendy; M. Gaytán | Zendy; C. Morales | Zendy; Raúl Gómez | Zendy; Francisco Gaytán | Zendy

Open Access

Superficial ovarian cortex vascularization is inversely related to the follicle reserve in normal cycling ovaries and is increased in polycystic ovary syndrome

Author(s) -

Francisco Delgado-Rosas,

M. Gaytán,

C. Morales,

Raúl Gómez,

Francisco Gaytán

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep008

Subject(s) - ovarian cortex , ovary , polycystic ovary , biology , stroma , medicine , endocrinology , follicle , ovarian follicle , antral follicle , cortex (anatomy) , ovarian reserve , andrology , infertility , pregnancy , immunohistochemistry , insulin resistance , genetics , ovarian tissue , neuroscience , insulin

The superficial ovarian cortex constitutes the micro-environment where resting and early growing follicles reside. As small follicles do not possess an independent capillary network, both their survival and early growth depend on their proximity to the cortical vessels. Little is known about the possible changes in superficial ovarian cortex vascularization in normal women throughout reproductive life or in pathological conditions such as polycystic ovary syndrome (PCOS) involving abnormal early follicle growth. We studied the vascularization of the superficial and deep cortical stroma (DCS) in normal cycling ovaries from 21 to 50 years of age and in infertile women with PCOS.

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