Down-regulation of p21-activated kinase 1 by progestin and its increased expression in the eutopic endometrium of women with endometriosis | Zendy

Sung Hoon Kim | Zendy; H. W. Lee | Zendy; Y. H. Kim | Zendy; Y. H. Koo | Zendy; HeeDong Chae | Zendy; C. H. Kim | Zendy; P. R. Lee | Zendy; B.-M. Kang | Zendy

Open Access

Down-regulation of p21-activated kinase 1 by progestin and its increased expression in the eutopic endometrium of women with endometriosis

Author(s) -

Sung Hoon Kim,

H. W. Lee,

Y. H. Kim,

Y. H. Koo,

HeeDong Chae,

C. H. Kim,

P. R. Lee,

B.-M. Kang

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den484

Subject(s) - endometriosis , endometrium , progestin , kinase , cancer research , medicine , andrology , endocrinology , biology , microbiology and biotechnology , hormone

P21-activated kinase 1 (Pak1) integrates various signaling pathways that are vital to cell survival and function. This study was performed to evaluate whether sex steroids may regulate the expression of Pak1 in endometrial cells as well as whether its expression is increased in the eutopic endometrium of women with endometriosis.

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