Prematuration of human denuded oocytes in a three-dimensional co-culture system: effects on meiosis progression and developmental competence | Zendy

Leen Vanhoutte | Zendy; D. M. Nogueira | Zendy; Petra De Sutter | Zendy

Open Access

Prematuration of human denuded oocytes in a three-dimensional co-culture system: effects on meiosis progression and developmental competence

Author(s) -

Leen Vanhoutte,

D. M. Nogueira,

Petra De Sutter

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den420

Subject(s) - in vitro maturation , germinal vesicle , oocyte , andrology , human fertilization , biology , meiosis , blastocyst , embryogenesis , embryo , chemistry , anatomy , microbiology and biotechnology , genetics , medicine , gene

During conventional in vitro maturation (IVM), oocytes undergo nuclear maturation but do not attain full cytoplasmic maturity. The present study aimed to evaluate the quality of denuded in vitro matured human oocytes (= 'rescue IVM') following a prematuration culture (PMC) in a three-dimensional (3D) co-culture system with cumulus cells.

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