Does controlled ovarian stimulation prior to chemotherapy increase primordial follicle loss and diminish ovarian reserve? An animal study | Zendy

Ettie Maman | Zendy; K. Prokopis | Zendy; Jacob Levron | Zendy; A. Carmely | Zendy; Dor J | Zendy; Dror Meirow | Zendy

Open Access

Does controlled ovarian stimulation prior to chemotherapy increase primordial follicle loss and diminish ovarian reserve? An animal study

Author(s) -

Ettie Maman,

K. Prokopis,

Jacob Levron,

A. Carmely,

Dor J,

Dror Meirow

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den337

Subject(s) - ovarian reserve , chemotherapy , fertility preservation , oocyte , ovary , stimulation , ovarian follicle , biology , physiology , medicine , fertility , andrology , embryo , gynecology , endocrinology , oncology , pregnancy , infertility , population , genetics , environmental health , microbiology and biotechnology

Storage of embryos for fertility preservation before chemotherapy is widely practiced. For multiple oocyte collection, the ovaries are hyperstimulated with gonadotrophins that significantly alter ovarian physiology. The effects of ovarian stimulation prior to chemotherapy on future ovarian reserve were investigated in an animal model.

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