Open AccessExpression of stathmin, a microtubule regulatory protein, is associated with the migration and differentiation of cultured early trophoblasts
Author(s) -
Mikihiro Yoshie,
Hideaki Kashima,
Toshio Bessho,
Makoto Takeichi,
Keiichi Isaka,
Kazuhiro Tamura
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den317
Subject(s) - stathmin , gene knockdown , trophoblast , biology , syncytiotrophoblasts , gene silencing , microbiology and biotechnology , small interfering rna , placentation , cell growth , cell culture , placenta , transfection , microtubule , fetus , gene , genetics , pregnancy
The microtubule-destabilizing protein stathmin is expressed by the villous cytotrophoblasts and invasive extravillous trophoblasts (EVTs) in the first-trimester human placenta. Here, we evaluated the significance of stathmin expression in terms of the functions of trophoblasts.