Pubertal development in children and adolescents born after IVF and spontaneous conception
Author(s) -
Ma Ceelen,
Mirjam M. van Weissenbruch,
Jan P.W. Vermeiden,
Flora E. van Leeuwen,
H.A. Delemarrevan de Waal
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den309
Subject(s) - menarche , medicine , fertility , gynecology , breast development , population , infertility , pregnancy , obstetrics , pediatrics , hormone , endocrinology , biology , environmental health , genetics
Previous studies demonstrated a link between adverse conditions during prenatal life and the development of diseases in adult life. It is still unclear whether IVF conception could permanently affect early prenatal development in humans, with post-natal health consequences. The objective of the present study is to examine pubertal development in 8-18-year-old IVF singletons and controls born from subfertile parents who attended one Dutch fertility clinic were included.
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