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Naltrexone treatment in clomiphene resistant women with polycystic ovary syndrome
Author(s) -
Mohamed I. Ahmed,
Antoni J. Dulęba,
O. El Shahat,
Mohamed Ibrahim,
A.A. Salem
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den273
Subject(s) - naltrexone , polycystic ovary , medicine , luteinizing hormone , hyperandrogenism , endocrinology , anovulation , gynecology , insulin resistance , opioid , hormone , insulin , receptor
Endogenous opiates may affect various aspects of reproductive and metabolic function in patients with polycystic ovary syndrome (PCOS). This study evaluated long-term inhibition of the opioid system using naltrexone in clomiphene citrate (CC)-resistant women with PCOS.

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