Metformin improves endothelial function in normoinsulinemic PCOS patients: a new prospective
Author(s) -
Daniela Romualdi,
Barbara Costantini,
L. Selvaggi,
Maddalena Giuliani,
Francesca Cristello,
F. Macrì,
A Bompiani,
Antonio Lanzone,
Maurizio Guido
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den230
Subject(s) - metformin , polycystic ovary , medicine , population , endocrinology , prospective cohort study , gynecology , diabetes mellitus , insulin resistance , environmental health
Metformin was reported to improve the alterations of endothelial reactivity in normal-weight subjects with polycystic ovary syndrome (PCOS). The aim of the present study was to investigate the mechanisms of action of this drug on the vascular function of this population.
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