Evaluation of the efficacy of a danazol-loaded intrauterine contraceptive device on adenomyosis in an ICR mouse model | Zendy

X. Zhang | Zendy; Yuan Huang | Zendy; Liping Deng | Zendy; Fengling Hu | Zendy; Jing Ma | Zendy; Jinwen Lin | Zendy

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Evaluation of the efficacy of a danazol-loaded intrauterine contraceptive device on adenomyosis in an ICR mouse model

Author(s) -

X. Zhang,

Yuan Huang,

Liping Deng,

Fengling Hu,

Jing Ma,

Jinwen Lin

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den208

Subject(s) - danazol , adenomyosis , medicine , endometriosis , urology , h&e stain , gynecology , pathology , staining

Danazol, a synthetic steroid with antigonadotrophic properties, has been widely used for the treatment of endometriosis and adenomyosis. However, the local application of danazol to the uterus to treat adenomyosis is controversial. The objective of this study is to develop an effective treatment for adenomyosis using danazol via intrauterine contraceptive device (IUCD) delivery.

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