The developing human ovary: immunohistochemical analysis of germ-cell-specific VASA protein, BCL-2/BAX expression balance and apoptosis | Zendy

Mirta S Albamonte | Zendy; Maria A. Willis | Zendy; María Itatí Albamonte | Zendy; Federico Jensen | Zendy; María Beatriz Espinosa | Zendy; Alfredo Daniel Vitullo | Zendy

Open Access

The developing human ovary: immunohistochemical analysis of germ-cell-specific VASA protein, BCL-2/BAX expression balance and apoptosis

Author(s) -

Mirta S Albamonte,

Maria A. Willis,

María Itatí Albamonte,

Federico Jensen,

María Beatriz Espinosa,

Alfredo Daniel Vitullo

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den197

Subject(s) - germ cell , apoptosis , ovary , biology , immunohistochemistry , programmed cell death , dna fragmentation , organogenesis , microbiology and biotechnology , andrology , endocrinology , immunology , medicine , genetics , gene

Germ cell number during ovarian organogenesis is regulated through programmed cell death. We investigated the expression of germ-cell-specific VASA protein, apoptosis-related proteins BAX and BCL-2 and DNA fragmentation in developing human ovaries from gestation week 12 to term.

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