Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach | Zendy

Véronique Thimon | Zendy; Gilles Frenette | Zendy; Fabrice Saez | Zendy; M. Thabet | Zendy; R Sullivan | Zendy

Open Access

Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach

Author(s) -

Véronique Thimon,

Gilles Frenette,

Fabrice Saez,

M. Thabet,

R Sullivan

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den181

Subject(s) - vesicle , proteome , seminal vesicle , western blot , population , biology , epididymis , vas deferens , blot , rete testis , proteomics , vasectomy , secretory protein , sperm , microbiology and biotechnology , anatomy , biochemistry , prostate , medicine , secretion , gene , genetics , cancer , membrane , family planning , research methodology , environmental health

The epididymal epithelium secretes membranous vesicles, called epididymosomes, with which a complex mixture of proteins is associated. These vesicles transfer to spermatozoa selected proteins involved in sperm maturation. Epididymosomes in the human excurrent duct have been described, but their protein composition and possible functions are unknown.

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