Endometriosis is associated with aberrant endometrial expression of telomerase and increased telomere length
Author(s) -
Dharani K. Hapangama,
M. Turner,
Josephine Drury,
Siobhan Quenby,
Gabriele Saretzki,
Carmen MartinRuiz,
Thomas von Zglinicki
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den172
Subject(s) - telomerase , endometriosis , endometrium , immunostaining , luteal phase , telomere , menstrual cycle , stromal cell , estrogen , telomerase reverse transcriptase , biology , immunohistochemistry , medicine , endocrinology , andrology , follicular phase , hormone , dna , biochemistry , genetics , gene
In order to test our hypothesis that endometriosis is associated with abnormal expression of telomerase and telomere lengthening in endometrium, we assessed endometrial expression of the human telomerase enzyme and telomere length (TL).
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