A comparison of sperm aneuploidy rates between infertile men with normal and abnormal karyotypes | Zendy

Gordon Kirkpatrick | Zendy; K. Ferguson | Zendy; H. Gao | Zendy; Steven S. Tang | Zendy; Victor Chow | Zendy; Basil Ho Yuen | Zendy; Sai Ma | Zendy

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A comparison of sperm aneuploidy rates between infertile men with normal and abnormal karyotypes

Author(s) -

Gordon Kirkpatrick,

K. Ferguson,

H. Gao,

Steven S. Tang,

Victor Chow,

Basil Ho Yuen,

Sai Ma

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den126

Subject(s) - aneuploidy , semen , biology , sperm , male infertility , andrology , karyotype , infertility , semen analysis , chromosome , genetics , pregnancy , medicine , gene

Abnormal semen parameters in chromosomally normal men are an indicator of an increased risk of sperm aneuploidy. Male carriers of chromosomal rearrangements may also display an increase in sperm aneuploidy for chromosomes not involved in the rearrangement, known as an interchromosomal effect (ICE), and this may be related to the impaired semen parameters of these men.

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