Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias | Zendy

Shinichi Ban | Zendy; Fumihiro Sata | Zendy; Norie Kurahashi | Zendy; Setsuko Kasai | Zendy; Kiyoshi Moriya | Zendy; Hidehiro Κakizaki | Zendy; Katsuya omura | Zendy; Reiko Kishi | Zendy

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Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias

Author(s) -

Shinichi Ban,

Fumihiro Sata,

Norie Kurahashi,

Setsuko Kasai,

Kiyoshi Moriya,

Hidehiro Κakizaki,

Katsuya omura,

Reiko Kishi

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den098

Subject(s) - hypospadias , estrogen , estrogen receptor alpha , medicine , endocrinology , estrogen receptor , surgery , cancer , breast cancer

The etiology of hypospadias is regarded as a complex disorder with both genetic and environmental contributions. Although alterations in androgen activity have been associated with hypospadias, few associations with estrogen activity have been documented. Here, we assessed genetic polymorphisms in estrogen receptor genes and their association with hypospadias.

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