Open AccessIsolation of human single chain variable fragment antibodies against specific sperm antigens for immunocontraceptive development
Author(s) -
Arthur Sylvester Samuel,
Rajesh K. Naz
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den088
Subject(s) - antigen , antibody , sperm , biology , epitope , monoclonal antibody , phage display , antibody repertoire , microbiology and biotechnology , immunoglobulin light chain , immunology , genetics
Contraceptive vaccines can provide valuable alternatives to current methods of contraception. We describe here the development of sperm-reactive human single chain variable fragment (scFv) antibodies of defined sperm specificity for immunocontraception.
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