Higher incidence of linked malformations in siblings of Mayer-Rokitansky-Kuster-Hauser-syndrome patients | Zendy

M. Wottgen | Zendy; SY Brucker | Zendy; Stefan P. Renner | Zendy; Pamela L. Strissel | Zendy; Reiner Strick | Zendy; Anja Kellermann | Zendy; D. Wallwiener | Zendy; Matthias W. Beckmann | Zendy; Patricia G. Oppelt | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Higher incidence of linked malformations in siblings of Mayer-Rokitansky-Kuster-Hauser-syndrome patients

Author(s) -

M. Wottgen,

SY Brucker,

Stefan P. Renner,

Pamela L. Strissel,

Reiner Strick,

Anja Kellermann,

D. Wallwiener,

Matthias W. Beckmann,

Patricia G. Oppelt

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den059

Subject(s) - etiology , medicine , genitourinary system , incidence (geometry) , mayer rokitansky kuster hauser syndrome , sex organ , population , gynecology , pediatrics , obstetrics , uterus , pathology , biology , physics , environmental health , optics , genetics

Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a malformation of the female genital tract (vaginal aplasia, rudimentary uterus, normal fallopian tubes and high ovaries). The incidence is one in 4000 female newborns. The aim of the present study was to record genital and associated malformations among siblings and relatives of MRKH patients in order to draw possible conclusions regarding the etiology of the syndrome: heredity (dominant versus recessive) or spontaneous malformation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research