Identification of differentially expressed markers in human follicular cells associated with competent oocytes | Zendy

Mélanie Hamel | Zendy; Isabelle Dufort | Zendy; Claude Robert | Zendy; Catherine Gravel | Zendy; Marie-Claude Léveillé | Zendy; Arthur Leader | Zendy; MarcAndré Sirard | Zendy

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Identification of differentially expressed markers in human follicular cells associated with competent oocytes

Author(s) -

Mélanie Hamel,

Isabelle Dufort,

Claude Robert,

Catherine Gravel,

Marie-Claude Léveillé,

Arthur Leader,

MarcAndré Sirard

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/den048

Subject(s) - biology , andrology , follicular phase , oocyte , transcriptome , suppression subtractive hybridization , microarray analysis techniques , embryo , microarray , ovarian follicle , gene expression profiling , microbiology and biotechnology , genetics , gene , cdna library , complementary dna , gene expression , medicine

The development of an accurate method for selection of high-quality embryos is essential to achieve high pregnancy rates with single embryo transfer in human IVF. The developmental competence of the oocyte is acquired during follicle maturation and strong communication also exists between the follicular cells (FCs) and the oocytes; thus oocyte developmental competence may be determined by markers expressed in the surrounding FCs.

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