L1 cell adhesion molecule (L1CAM) as a pathogenetic factor in endometriosis
Author(s) -
D. Finas,
Monica Huszar,
A. Agic,
S. Dogan,
Helena Kiefel,
Svenja Riedle,
Daniela Gast,
Robert Marcovich,
F. Noack,
Peter Altevogt,
Mina Fogel,
Daniela Hornung
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den044
Subject(s) - endometriosis , l1 , cell adhesion molecule , medicine , clear cell , ovarian cancer , endometrial cancer , cell adhesion , disease , cancer research , cancer , oncology , cell , pathology , gynecology , carcinoma , biology , immunology , human papillomavirus , genetics
Endometriosis is a benign and progressive disease with a high prevalence. Women with endometriosis, especially with atypical endometriosis, have a higher probability for developing ovarian cancer compared with women without endometriosis. The L1 cell adhesion molecule (L1CAM) is over expressed in ovarian and endometrial carcinomas and is associated with a bad prognosis. Here, we have analysed L1CAM expression in endometriosis.
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