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Coelomic cells show apoptosis via Fas/FasL system: a comparative study between healthy human pregnancies and missed miscarriages
Author(s) -
Apostolos Kaponis,
A. Skyrlas,
Νεκταρία Ζαγοριανάκου,
Ioannis Georgiou,
V. Passa,
E. Paraskevaidis,
George Makrydimas
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den031
Subject(s) - fas ligand , apoptosis , trophoblast , biology , andrology , programmed cell death , dna fragmentation , immunology , microbiology and biotechnology , medicine , fetus , pregnancy , placenta , biochemistry , genetics
The Fas/Fas ligand (FasL) system represents one of the main apoptotic pathways controlling placental apoptosis throughout gestation. In the current study, we have examined the Fas/FasL protein expression and the apoptotic incidents of coelomic cells, amniotic cells and trophoblastic tissue in first trimester human pregnancies and missed miscarriages (MM).

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