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A new rapid and effective method for treatment of unexplained infertility
Author(s) -
Greta Edelstam,
Anette Sjösten,
Kerstin Bjuresten,
Ingvar Ek,
Kjell Wånggren,
Jack Spira
Publication year - 2008
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/den003
Subject(s) - unexplained infertility , insemination , artificial insemination , infertility , pregnancy , obstetrics , ovulation , gynecology , pregnancy rate , medicine , clomifene , intrauterine insemination , fertility , ovulation induction , andrology , biology , sperm , population , genetics , environmental health
Artificial insemination (intrauterine insemination by husband or artificial insemination by husband) is often tried as first treatment for couples with unexplained infertility. Pertubation has previously proved to increase the chance of achieving pregnancy for these couples. The effect of pertubation on fertility can be mechanical as well as anti-inflammatory by using a substance that inhibits phagocytosis of the spermatozoa.The objective of the study was to investigate the effect on pregnancy rate of pre-ovulatory pertubation with low-dose lignocaine during clomiphene citrate and insemination cycles for couples with unexplained infertility.

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