Ovarian tissue viability following whole ovine ovary cryopreservation: assessing the effects of sphingosine-1-phosphate inclusion | Zendy

V.J. Onions | Zendy; Marci R. Mitchell | Zendy; Bruce Campbell | Zendy; R. Webb | Zendy

Open Access

Ovarian tissue viability following whole ovine ovary cryopreservation: assessing the effects of sphingosine-1-phosphate inclusion

Author(s) -

V.J. Onions,

Marci R. Mitchell,

Bruce Campbell,

R. Webb

Publication year - 2008

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem414

Subject(s) - cryopreservation , andrology , viability assay , trypan blue , biology , ovarian tissue cryopreservation , ovary , fertility preservation , apoptosis , endocrinology , medicine , microbiology and biotechnology , biochemistry , embryo , fertility , population , environmental health

Cryopreservation is hypothesized to result in apoptosis, contributing to stromal damage and follicle loss in ovarian tissue. This study investigated tissue viability following whole ovine ovary cryopreservation and examined the effects of the anti-apoptotic agent sphingosine-1-phosphate (S-1-P) on ovarian cryopreservation efficiency.

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