Adverse reproductive outcomes in urban women with adeno-associated virus-2 infections in early pregnancy | Zendy

Fabián Arechavaleta-Velasco | Zendy; Luis M. Gómez | Zendy; Yujie Ma | Zendy; Jing Zhao | Zendy; Cindy McGrath | Zendy; Mary D. Sammel | Zendy; David Nelson | Zendy; Samuel Parry | Zendy

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Adverse reproductive outcomes in urban women with adeno-associated virus-2 infections in early pregnancy

Author(s) -

Fabián Arechavaleta-Velasco,

Luis M. Gómez,

Yujie Ma,

Jing Zhao,

Cindy McGrath,

Mary D. Sammel,

David Nelson,

Samuel Parry

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem360

Subject(s) - pregnancy , adeno associated virus , trophoblast , adverse effect , medicine , obstetrics , placenta , fetus , biology , vector (molecular biology) , genetics , gene , recombinant dna

We demonstrated recently that adeno-associated virus-2 (AAV-2) DNA was detected significantly more frequently in placental trophoblast cells from cases of severe pre-eclampsia than from normal term deliveries. Here, we sought to determine if maternal AAV-2 infection early in pregnancy preceded adverse outcomes resulting from placental dysfunction.

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