Laser-assisted derivation of human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis | Zendy

Tikva Turetsky | Zendy; Elias Aizenman | Zendy; Yaniv Gil | Zendy; N. Weinberg | Zendy; Yoel Shufaro | Zendy; Ariel Revel | Zendy; Neri Laufer | Zendy; Alex Simon | Zendy; Dvorah Abeliovich | Zendy; Benjamin Reubinoff | Zendy

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Laser-assisted derivation of human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis

Author(s) -

Tikva Turetsky,

Elias Aizenman,

Yaniv Gil,

N. Weinberg,

Yoel Shufaro,

Ariel Revel,

Neri Laufer,

Alex Simon,

Dvorah Abeliovich,

Benjamin Reubinoff

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem351

Subject(s) - inner cell mass , preimplantation genetic diagnosis , biology , embryonic stem cell , blastocyst , chimera (genetics) , induced pluripotent stem cell , embryo , stem cell , zona pellucida , microbiology and biotechnology , andrology , genetics , embryogenesis , medicine , gene , oocyte

Human embryonic stem cells (hESCs) suitable for future transplantation therapy should preferably be developed in an animal-free system. Our objective was to develop a laser-based system for the isolation of the inner cell mass (ICM) that can develop into hESC lines, thereby circumventing immunosurgery that utilizes animal products.

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