Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease | Zendy

Fatma Ferda Verit | Zendy; Özcan Erel | Zendy; Nilüfer Çelik | Zendy

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Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease

Author(s) -

Fatma Ferda Verit,

Özcan Erel,

Nilüfer Çelik

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem340

Subject(s) - endometriosis , paraoxonase , medicine , endocrinology , oxidative stress , triglyceride , pon1 , pathophysiology , lipoprotein , cholesterol , biology , biochemistry , genotype , gene

There is increasing evidence that oxidative stress may play a role in the pathophysiology of endometriosis. Serum paraoxonase-1 (PON-1) is a high-density lipoprotein (HDL) associated enzyme that prevents oxidative modification of low-density lipoprotein (LDL). The aims of the study were to (i) compare the serum PON-1 activity in women with endometriosis versus controls and (ii) assess whether PON-1 activity can be used as a diagnostic test for endometriosis.

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