Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis | Zendy

V. Goossens | Zendy; Martine De Rycke | Zendy; A. De Vos | Zendy; C. Staessen | Zendy; A. Michiels | Zendy; Willem Verpoest | Zendy; A. Van Steirteghem | Zendy; Claude Bertrand | Zendy; I. Liebaers | Zendy; Paul Devroey | Zendy; Karen Sermon | Zendy

Open Access

Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis

Author(s) -

V. Goossens,

Martine De Rycke,

A. De Vos,

C. Staessen,

A. Michiels,

Willem Verpoest,

A. Van Steirteghem,

Claude Bertrand,

I. Liebaers,

Paul Devroey,

Karen Sermon

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem327

Subject(s) - blastomere , biopsy , preimplantation genetic diagnosis , embryo , live birth , confidence interval , biology , andrology , pregnancy , gynecology , embryogenesis , medicine , pathology , genetics

Preimplantation genetic diagnosis or screening (PGD, PGS) involves embryo biopsy on Day 3. Opting for one- or two-cell biopsy is a balance between the lowest risk for misdiagnosis on the one hand and the highest chance for a pregnancy on the other hand.

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