High oxygen atmosphere improves human follicle development in organ cultures of ovarian cortical tissues in vitro
Author(s) -
Yoshiharu Morimoto,
Yusuke Oku,
M. Sonoda,
A. Haruki,
Ko Ito,
S. Hashimoto,
Aisaku Fukuda
Publication year - 2007
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dem314
Subject(s) - organ culture , ovary , tissue culture , biology , ovarian cortex , ovarian follicle , andrology , follicle , in vitro , medicine , endocrinology , ovarian tissue , biochemistry
Obtaining mature human follicles from cultured ovarian tissue may be beneficial for clinical use for women who wish to preserve fertile competence. However, the methodology of culture such as culture condition and gas atmosphere has not been well established in humans. Therefore, we investigated the effect of oxygen concentration in organ culture in order to establish an ovarian tissue culture method.
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