Human sperm express a functional androgen receptor: effects on PI3K/AKT pathway | Zendy

Saveria Aquila | Zendy; Emilia Middea | Zendy; Stefania Catalano | Zendy; Stefania Marsico | Zendy; Marilena Lanzino | Zendy; Ivan Casaburi | Zendy; Ines Barone | Zendy; Roberto Bruno | Zendy; S. Zupo | Zendy; Sebastiano Andò | Zendy

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Human sperm express a functional androgen receptor: effects on PI3K/AKT pathway

Author(s) -

Saveria Aquila,

Emilia Middea,

Stefania Catalano,

Stefania Marsico,

Marilena Lanzino,

Ivan Casaburi,

Ines Barone,

Roberto Bruno,

S. Zupo,

Sebastiano Andò

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem243

Subject(s) - protein kinase b , pi3k/akt/mtor pathway , wortmannin , androgen receptor , pten , biology , endocrinology , phosphorylation , chemistry , medicine , microbiology and biotechnology , signal transduction , prostate cancer , cancer

Results from mice lacking the androgen receptor (AR) showed that it is critical for the proper development and function of the testes. The aim of this study was to investigate whether a functional AR is present in human sperm.

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