Progesterone withdrawal up-regulates fibronectin and integrins during menstruation and repair in the rhesus macaque endometrium
Author(s) -
Wen-Qing Cao,
Kar Men Mah,
Rebecca S. Carroll,
Ov D. Slayden,
Robert Brenner
Publication year - 2007
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dem216
Subject(s) - endometrium , fibronectin , stromal cell , biology , endocrinology , medicine , extracellular matrix , macaque , progesterone receptor , in situ hybridization , integrin , luteal phase , menstruation , epithelium , receptor , andrology , follicular phase , gene expression , estrogen receptor , microbiology and biotechnology , neuroscience , biochemistry , genetics , cancer , breast cancer , gene
Fibronectin (FN) is a component of the extracellular matrix that participates in wound healing in various tissues as an adhesive ligand for integrins (Itgs). To determine whether these molecules play similar roles during menstrual repair, we evaluated the expression and localization of FN and specific Itgs in the primate endometrium under hormonally controlled conditions.
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