Open AccessGenome-wide expression analysis of cultured trophoblast with trisomy 21 karyotype
Author(s) -
Uri Rozovski,
Anat Jonish-Grossman,
Anat BarShira,
Yifat Ochshorn,
Myriam Goldstein,
Yuval Yaron
Publication year - 2007
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dem214
Subject(s) - karyotype , trisomy , trophoblast , biology , genetics , genome , chromosome , andrology , pregnancy , medicine , placenta , gene , fetus
The pathologic features of Down syndrome are assumed to be the result of over-expression of genes located on chromosome 21 and/or a more global transcriptional misregulation that crosses chromosomal borders.
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