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Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample
Author(s) -
Zhen Zhao,
Dale R. Nyholt,
Long Ho Le,
Shane Thomas,
Christian Engwerda,
Louise M. Randall,
Susan A. Treloar,
Grant W. Montgomery
Publication year - 2007
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dem182
Subject(s) - single nucleotide polymorphism , lymphotoxin alpha , haplotype , snp , endometriosis , international hapmap project , biology , lymphotoxin , snp genotyping , tag snp , candidate gene , genotype , genetics , genetic association , gene , medicine , cytokine
Tumour necrosis factor (TNF) is a pleiotropic cytokine with a wide range of immunoregulatory effects. Variation in the promoter region of TNF and the neighbouring lymphotoxin alpha (LTA) gene might be associated with endometriosis.

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