Azoospermic HIV-1 infected patients wishing to have children: proposed strategy to reduce HIV-1 transmission risk during sperm retrieval and intracytoplasmic sperm injection: Case Report | Zendy

Louis Bujan | Zendy; Myriam Daudin | Zendy; Nathalie Moinard | Zendy; Pierre Plante | Zendy; Jean Parinaud | Zendy; Christophe Pasquier | Zendy

Open Access

Azoospermic HIV-1 infected patients wishing to have children: proposed strategy to reduce HIV-1 transmission risk during sperm retrieval and intracytoplasmic sperm injection: Case Report

Author(s) -

Louis Bujan,

Myriam Daudin,

Nathalie Moinard,

Pierre Plante,

Jean Parinaud,

Christophe Pasquier

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem175

Subject(s) - intracytoplasmic sperm injection , sperm retrieval , sperm , human immunodeficiency virus (hiv) , sperm washing , transmission (telecommunications) , gynecology , medicine , andrology , biology , infertility , virology , pregnancy , computer science , genetics , insemination , telecommunications

To date, assisted reproductive technology (ART) with sperm washing is offered to serodiscordant couples with an human immunodeficiency virus-1 (HIV-1) infected male partner in order to have a child while reducing the risk of transmission to the woman. However, ART programmes are not possible if the man is azoospermic. We report here the first birth following intracytoplasmic sperm injection (ICSI) using frozen epididymal spermatozoa obtained after surgical sperm retrieval in a HIV-1 infected man with obstructive azoospermia. METHODS; Sperm obtained by micro-epididymal sperm aspiration was frozen after density gradient preparation and tested for HIV-RNA and DNA. ICSI with frozen sperm was performed.

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