Effects of supplemental perioperative oxygen on post-operative abdominal wound adhesions in a mouse laparotomy model with controlled respiratory support | Zendy

Sachiko Matsuzaki | Zendy; М. Canis | Zendy; J. E. Bazin | Zendy; Claude Darcha | Zendy; Jean Luc Pouly | Zendy; G. Mage | Zendy

Open Access

Effects of supplemental perioperative oxygen on post-operative abdominal wound adhesions in a mouse laparotomy model with controlled respiratory support

Author(s) -

Sachiko Matsuzaki,

М. Canis,

J. E. Bazin,

Claude Darcha,

Jean Luc Pouly,

G. Mage

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem114

Subject(s) - laparotomy , perioperative , medicine , supplemental oxygen , surgery , anesthesia

Post-operative adhesion formation is a major clinical problem. Tissue oxygenation is one of the most important determinants in adhesion formation. The objective of this study was to investigate whether supplemental perioperative oxygen could reduce post-operative adhesion formation through increasing the peritoneal tissue oxygen tension (PitO(2)) in a mouse model.

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