Polymorphism in the insulin-like growth factor 1 gene is associated with age at menarche in caucasian females | Zendy

Jian Zhao | Zendy; Dong-Hai Xiong | Zendy; Yan Guo | Zendy; TieLin Yang | Zendy; Robert R. Recker | Zendy; HongWen Deng | Zendy

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Polymorphism in the insulin-like growth factor 1 gene is associated with age at menarche in caucasian females

Author(s) -

Jian Zhao,

Dong-Hai Xiong,

Yan Guo,

TieLin Yang,

Robert R. Recker,

HongWen Deng

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dem052

Subject(s) - linkage disequilibrium , single nucleotide polymorphism , haplotype , menarche , snp , transmission disequilibrium test , biology , genetics , genetic association , medicine , endocrinology , genotype , gene

The insulin-like growth factor 1 (IGF1) gene, which plays a crucial role in hypothalamic-pituitary-ovarian hormone-controlled metabolic processes, may influence the onset of menarche. Our study aimed to test association between IGF1 polymorphisms with the variation of age at menarche (AAM) in Caucasian females.

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