Blastocyst biopsy versus cleavage stage biopsy and blastocyst transfer for preimplantation genetic diagnosis of β-thalassaemia: a pilot study | Zendy

Georgia Kokkali | Zendy; Joanne TraegerSynodinos | Zendy; Christina Vrettou | Zendy; D. Stavrou | Zendy; Gayle M Jones | Zendy; David S. Cram | Zendy; Evangelos Makrakis | Zendy; Alan Trounson | Zendy; Emmanouel Kanavakis | Zendy; Konstantinos Pantos | Zendy

Open Access

Blastocyst biopsy versus cleavage stage biopsy and blastocyst transfer for preimplantation genetic diagnosis of β-thalassaemia: a pilot study

Author(s) -

Georgia Kokkali,

Joanne TraegerSynodinos,

Christina Vrettou,

D. Stavrou,

Gayle M Jones,

David S. Cram,

Evangelos Makrakis,

Alan Trounson,

Emmanouel Kanavakis,

Konstantinos Pantos

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/del506

Subject(s) - blastocyst , blastomere , blastocyst transfer , biopsy , preimplantation genetic diagnosis , embryo transfer , andrology , gynecology , biology , embryo , medicine , obstetrics , embryogenesis , pathology , genetics

Trophectoderm biopsy at the blastocyst stage is an emerging approach in preimplantation genetic diagnosis (PGD). This study aimed to compare genotyping success and implantation rates in PGD cycles for beta-thalassaemia following biopsy at the cleavage versus the blastocyst stage, with transfer of blastocysts.

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