Cyclooxygenase enzyme expression and E series prostaglandin receptor signalling are enhanced in heavy menstruation | Zendy

Oliver P. Milling Smith | Zendy; Henry N. Jabbour | Zendy; Hilary Critchley | Zendy

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Cyclooxygenase enzyme expression and E series prostaglandin receptor signalling are enhanced in heavy menstruation

Author(s) -

Oliver P. Milling Smith,

Henry N. Jabbour,

Hilary Critchley

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/del503

Subject(s) - cyclooxygenase , prostaglandin , endometrium , menstruation , receptor , menstrual cycle , endocrinology , medicine , biology , enzyme , chemistry , microbiology and biotechnology , biochemistry , hormone

Although the mechanisms underlying the causes of heavy menstrual blood loss (MBL) remain to be elucidated, prostaglandins have been previously implicated. This study was initiated to elucidate a pattern of expression of the various components of the cyclooxygenase (COX)-prostaglandin signalling pathways present in the endometrium of women with normal and heavy MBLs.

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