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A comparative study of the effect of continuous combined conjugated equine estrogen plus medroxyprogesterone acetate and tibolone on blood coagulability
Author(s) -
Sven O. Skouby,
Johannes Jakobsen Sidelmann,
Lisbeth Nilas,
Jørgen Jespersen
Publication year - 2007
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del498
Subject(s) - tibolone , medroxyprogesterone acetate , medicine , medroxyprogesterone , endocrinology , estrogen , tissue factor pathway inhibitor , menopause , antithrombin , coagulation , heparin , tissue factor
Hormone therapy (HT) after the menopause is associated with increased risk of venous thromboembolism (VTE). Tibolone has pharmacodynamic properties different from other hormone preparations. We compared the effect of a combined HT and tibolone on the inhibition of haemostasis.

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