Sperm quality and pregnancy rate after COX-2 inhibitor therapy of infertile males with abacterial leukocytospermia | Zendy

Laura Gambera | Zendy; Francesca Serafini | Zendy; Giuseppe Morgante | Zendy; Riccardo Focarelli | Zendy; Vincenzo De Leo | Zendy; Paola Piomboni | Zendy

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Sperm quality and pregnancy rate after COX-2 inhibitor therapy of infertile males with abacterial leukocytospermia

Author(s) -

Laura Gambera,

Francesca Serafini,

Giuseppe Morgante,

Riccardo Focarelli,

Vincenzo De Leo,

Paola Piomboni

Publication year - 2007

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/del490

Subject(s) - rofecoxib , pregnancy rate , pregnancy , andrology , gynecology , insemination , sperm quality , medicine , intrauterine insemination , sperm , cyclooxygenase , biology , biochemistry , genetics , enzyme

Leukocytes are a frequent finding in seminal plasma of infertile males with abacterial inflammation. We evaluated the effects of treatment with rofecoxib, a cyclooxygenase-2 inhibitor, on sperm quality and pregnancy rate after intrauterine insemination (IUI) or monitored intercourse.

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