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Malformation rate and sex ratio in 412 children conceived with epididymal or testicular sperm
Author(s) -
Jens Fedder,
Anette Gabrielsen,
Peter Humaidan,
Karin Erb,
Erik Ernst,
Anne Gitte Loft
Publication year - 2007
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del488
Subject(s) - hypospadias , sperm , medicine , gynecology , intracytoplasmic sperm injection , confidence interval , population , human fertilization , obstetrics , sex ratio , sperm retrieval , infertility , andrology , pregnancy , biology , surgery , environmental health , anatomy , genetics
Follow-up studies of children conceived after ICSI using epididymal or testicular sperm are important due to a still more extensive use of immature male germ cells for ICSI. It is, however, difficult to evaluate the potential risks of malformations of children born after ICSI, overcoming the natural fertilization processes, due to methodological limitations.

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