A successful IVF–pregnancy in a patient who underwent conservative surgery followed by a regimen of cisplatin, vinblastine and peplomycin to treat an advanced ovarian mixed germ cell tumour: A Case Report | Zendy

Yuka Kitajima | Zendy; Tomoyoshi Endo | Zendy; Takako Hayashi | Zendy; S Ishioka | Zendy; Tsuyoshi Baba | Zendy; Hiroyuki Honnma | Zendy; Taeko Saito | Zendy

Open Access

A successful IVF–pregnancy in a patient who underwent conservative surgery followed by a regimen of cisplatin, vinblastine and peplomycin to treat an advanced ovarian mixed germ cell tumour: A Case Report

Author(s) -

Yuka Kitajima,

Tomoyoshi Endo,

Takako Hayashi,

S Ishioka,

Tsuyoshi Baba,

Hiroyuki Honnma,

Taeko Saito

Publication year - 2006

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/del413

Subject(s) - regimen , vinblastine , medicine , germ cell tumors , chemotherapy , cisplatin , reproductive medicine , germ cell , gynecology , surgery , pregnancy , biology , biochemistry , gene , genetics

Mixed germ cell tumours of the ovary, one type of malignant ovarian germ cell tumours (MOGCTs), are rare gynaecologic cancers usually affecting young women. We report the case of a patient with an advanced ovarian mixed germ cell tumour who underwent fertility-saving surgery followed by a chemotherapy regimen of cisplatin, vinblastine and peplomycin. The patient was disease-free 8 years after initial presentation. She conceived and gestated dichorionic twins after IVF-embryo transfer. To the best of our knowledge, the patient is the first to be treated successfully with the combination chemotherapy regimen and then conceive safely using assisted reproductive technology (ART).

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