Menstrual cycle-dependent changes of Toll-like receptors in endometrium
Author(s) -
Reza Aflatoonian,
E. Tuckerman,
Sarah L. Elliott,
C. Bruce,
Abbas Aflatoonian,
Tin Chiu Li,
Alireza Fazeli
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del388
Subject(s) - endometrium , menstrual cycle , receptor , toll , andrology , medicine , gynecology , biology , hormone , immunology
Rapid innate immune defences against infection usually involve the recognition of invading pathogens by specific pattern recognition receptors recently attributed to the family of Toll-like receptors (TLRs). Reports from our laboratory and others have demonstrated the existence of TLRs 1-6 in the female reproductive tract. However, little has been done to identify TLRs 7-10 in the female reproductive tract, particularly in the uterus. Also little information exists regarding variation in TLRs in the female reproductive tract during the menstrual cycle.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom