Open AccessSex-specific promoters regulate Dnmt3L expression in mouse germ cells
Author(s) -
Tanya C. Shovlin,
Déborah Bourc’his,
Sophie La Salle,
A. O’Doherty,
J.M. Trasler,
Timothy H. Bestor,
Colum P. Walsh
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del379
Subject(s) - biology , promoter , dna methylation , microbiology and biotechnology , genetics , genomic imprinting , gene , germ cell , gene expression
Dnmt3L, a member of the DNA methyltransferase 3 family, lacks enzymatic activity but is required for de-novo methylation of imprinted genes in oocytes and for transposon repression in male germ cells.
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